Discovery of novel heart rate-associated loci using the Exome Chip
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چکیده
Supplementary Material 1. Supplementary Figure Titles Supplementary Figure 1: Quantile-Quantile (QQ) plot of the discovery phase metaanalysis of RR-interval among the European-ancestry individuals. Supplementary Figure 2: (a) Comparison of the betas between the untransformed RR-interval meta-analysis and the inverse normalized RR-interval residuals (RR-INVN) meta-analysis; (b) Comparison of the P-values between the untransformed RRinterval meta-analysis and the inverse normalized RR-interval residuals (RR-INVN) meta-analysis. Supplementary Figure 3: (a) Histogram showing the distribution of RR-interval phenotype in the 1958BC study; (b) Quantile-Quantile (QQ) plot of RR-interval phenotype in the 1958BC study.
منابع مشابه
Discovery of novel heart rate-associated loci using the Exome Chip
Resting heart rate is a heritable trait, and an increase in heart rate is associated with increased mortality risk. Genome-wide association study analyses have found loci associated with resting heart rate, at the time of our study these loci explained 0.9% of the variation. This study aims to discover new genetic loci associated with heart rate from Exome Chip meta-analyses.Heart rate was meas...
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